Inotropic and chronotropic effects of antiarrhythmic agents onisolated blood-perfused canine ventricular tissue.

Recent advances in studies on cardiac structure and metabolism Pub Date : 1976-05-26

K Hashimoto, T Tsukada, H Matsuda

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Abstract

In the isolated blood-perfused canine ventricular tissue, antiarrhythmic agents could be classified as having: 1) positive chronotropic and inotropic effects (procainamide), 2) negative chronotropic but positive inotropic effects (quinidine), and 3) negative chronotropic and inotropic effects (lidocaine, ajmaline, diphenylhydantoin, and propranolol).

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抗心律失常药物对离体血灌注犬心室组织的肌力和变时作用。

在离体血灌注犬心室组织中，抗心律失常药物可分为:1)正性变时性和正性肌力作用(普鲁卡因胺)，2)负性变时性但正性肌力作用(奎尼丁)，3)负性变时性和正性肌力作用(利多卡因、ajmaline、二苯基氢妥英和心得安)。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Recent advances in studies on cardiac structure and metabolism

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