The circadian variations of the rates of excretion of urinary electrolytes and of deep body temperature.

D S Minors, J N Mills, J M Waterhouse
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Abstract

53 apparently healthy subjects were studied for control spans of between 60 and 184 hours while they followed a regular pattern of meals, ambulance and sleep before experiments on altered time schedules. Urine was collected and deep body temperature was measured every 2 hours while they were awake, and in some rectal temperature was also recorded during sleep. Urine was analysed for sodium, potassium, chloride, phosphate and creatinine and in 26 subjects also for calcium and uric acid. The rhythms of temperature, urine flow, and rate of excretion of each urinary solute, are presented as consinors. The two rhythms most closely linked were of excretion of chloride and sodium; the choloride acrophase led the sodium acrophase by one a half hours.

尿电解质排泄率和深体温的昼夜变化。
53名看似健康的受试者在60至184小时的控制期内接受了研究,在此期间,他们遵循有规律的饮食、救护车和睡眠模式,然后进行了改变时间安排的实验。在醒着时每2小时收集尿液并测量深体温,并在睡眠时记录部分患者的直肠温度。研究人员分析了26名受试者的尿液中钠、钾、氯、磷酸盐和肌酐的含量,以及钙和尿酸的含量。体温、尿流和每一种尿溶质的排泄率的节律,被作为参考。两种最密切相关的节律是氯和钠的排泄;氯化物的顶相比钠顶相早一个半小时。
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