Perinatal Outcome Of Pregnancies Complicated By Hypertensive Disorders At The University Of Benin Teaching Hospital, Benin City, Nigeria

Annals of Biomedical Sciences Pub Date : 2008-01-30 DOI:10.4314/ABS.V4I2.40674

A. N. Onyiriuka, A. Okolo

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Abstract

In this case-control study, we examined the perinatal outcome in 272 pregnancies complicated by hypertension and compared the result with that of 816 control cases. The overall prevalence of hypertensive disorders in pregnancy (HDP) was 7.2%. There was significantly higher perinatal mortality rate (PMR) of 110.3 per 1000 deliveries in hypertensive mothers compared with 33.0 per 1000 deliveries in normotensive mothers. Comparing the various subtypes of HDP, chronic hypertension with superimposed pre-eclampsia was associated with the highest PMR of 714.3 per 1000 deliveries. The rate of delivery of low birth weight and preterm infants were significantly higher in hypertensive compared with normotensive mother. Comparing hypertensive and normotensive mothers, the Caesarean delivery rate was 35.7% versus 26.6%. The incidence rate of birth asphyxia was significantly higher in babies of hypertensive mothers compared with babies of normotensive mothers. Proportionate intrauterine growth retardation was found in infants born to mothers with chronic hypertension in contrast to disproportionate form found in infants born to mothers with pregnancy-induced hypertension. In conclusion, HDP is associated with several adverse outcome such as premature birth, intrauterine growth restriction, birth asphyxia, fetal demise. Keywords : Hypertensive disorders in pregnancy; perinatal outcome. Annals of Biomedical Science Vol. 4 (1) 2005: pp. 25-34

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尼日利亚贝宁市贝宁大学教学医院妊娠合并高血压疾病的围产儿结局

在本病例对照研究中，我们检查了272例妊娠合并高血压的围产期结局，并将结果与816例对照病例进行了比较。妊娠期高血压疾病(HDP)的总患病率为7.2%。高血压母亲的围产期死亡率(PMR)为110.3‰，而正常母亲的围产期死亡率为33.0‰。比较各种HDP亚型，慢性高血压合并先兆子痫与最高的PMR相关，为714.3 / 1000次分娩。高血压母亲的低出生体重儿和早产率明显高于正常母亲。比较高血压母亲和正常母亲，剖腹产率分别为35.7%和26.6%。高血压母亲所生婴儿的出生窒息发生率明显高于正常母亲所生婴儿。慢性高血压母亲所生的婴儿存在不成比例的宫内发育迟缓，而妊娠高血压母亲所生的婴儿存在不成比例的宫内发育迟缓。总之，HDP与早产、宫内生长受限、出生窒息、胎儿死亡等不良结局相关。关键词:妊娠期高血压疾病;围产期结果。生物医学科学年鉴Vol. 4 (1) 2005: pp. 25-34

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Annals of Biomedical Sciences

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