Rhinocerebral Mucormycosis: an Unusual Presentation

A. Rajeshwari, Gangadhara Somayaji
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引用次数: 7

Abstract

Rhinocerebral mucormycosis is one of the most rapidly progressing and lethal form of fungal infection in humans which usually begins in the nose and paranasal sinuses and can extend to CNS. A 68 year old lady with poorly controlled diabetes presented with fever, disorientation, headache and left sided LMN type of facial palsy. ENT examination revealed a palatal ulcer and mucopus in middle meatus. MRI revealed an infarct in the territory of left superior cerebellar artery and haziness and mucosal thickening in the left maxillary and ethmoidal sinuses. Patient underwent endoscopic medial maxillectomy and debridement of palatal ulcer. Postoperative histopathology was suggestive of zygomycosis. Patient was subsequently treated with Amphotericin B for 4 weeks with good recovery. This case is being reported for its rarity as mucormycosis presenting with cerebellar signs has not been reported in the English literature so far.
鼻-脑毛霉菌病:一种不寻常的表现
鼻脑毛霉菌病是人类真菌感染中进展最迅速和最致命的形式之一,通常从鼻子和鼻窦开始,并可扩展到中枢神经系统。68岁女性糖尿病控制不佳,表现为发热、定向障碍、头痛和左侧LMN型面瘫。耳鼻喉科检查发现腭溃疡及中食管粘液。MRI示左侧小脑上动脉梗死,左侧上颌窦和筛窦模糊,粘膜增厚。病人接受内窥镜下上颌骨内侧切除术及腭溃疡清创。术后组织病理学提示为接合菌病。患者随后给予两性霉素B治疗4周,恢复良好。由于毛霉病表现为小脑体征,目前在英文文献中尚未报道,因此报道此病的罕见性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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