The Impact of Environmental Endocrine Disruptors on Mammalian Endocrine Systems and Hormonal Changes

Abstract

This study discusses the impact of the EDCS or environmental endocrine disruptors in the mammalian endocrine system and also in the hormonal changes. As the EDCs have a role to mimic the pathway and the activity of hormones then the detection method is the first and foremost important concern in this scenario. This study also reflects some detection assays of environmental endocrine disruptors by which their impact can be effectively understood. As EDCs alter the hormonal function then it can be said that beta lactamase activity is the main theme for detecting endocrine disruptors. Endocrine disrupting chemicals can be chosen in the human samples by using the biosensor protein. The final nitrocefin concentration effectively detects the activity of EDCs. The study also discusses some key aspects of changes of hormonal function by EDCs in gene and protein level. The gene and protein level study are beneficial in this scenario for understanding the mode of action of each and every type of environmental endocrine disruptors. The graph has been presented in this scenario for understanding the expression level of proteins. Keyword : Environmental endocrine disruptors, EDCs, biosensor protein, beta lactamase activity