Registry of aortic valve stenosis patients in delta region in Egypt

A. B. Zaid, Mohammed Elbarbary, S. Khalil, Timor Mostafa Abdullah
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Abstract

Background: The most widespread valvular heart disease in industrialised nations is aortic stenosis (AS), and its rate rises with age. In relation to the present causes, the purpose of this paper was to characterise the clinical features of AS patients in the Delta area of Egypt, diagnostic and treatment strategies to improve the care of those patients. Methods: This prospective, observational, multicenter registry research involved 700 patients with prosthetic aortic valves and clinical criteria for mild, moderate, and severe AS. Aortic-valve gradients of less than 25 mmHg were considered mild, 25-40 mmHg were judged moderate, and greater than 1 cm2 was deemed severe based on European Society of Cardiology (ESC) standards. Results: Regarding age 43% were males and 57% were females, the severity 12% moderate, and severe in 18%, 4% participants had prosthetic valve. Echocardiography showed that 41% of patients had left ventricular hypertrophy. The ejection fraction (EF) ranged from 36 to 70%, for Electrocardiogram, 68% had sinus rhythm, 18% had Atrial fibrillation, 10% had left Bundle branch block (BBB), and 4% had pathological Q wave, type of treatment was medical in 80% participants, and surgical in 13%, and Transcatheter aortic valve replacement (TAVI) in 1%, 2% participants refused surgery and 4% were medically non-fit for surgery. Conclusions: No pharmaceutical treatment is presently effective in minimising the development of AS, and patient-education efforts will see a spike in the rate of AS in the population who are 50 years old and older, in both sexes, TAVI and Screening programs should be initiated among AS patients.
埃及三角洲地区主动脉瓣狭窄患者登记
背景:在工业化国家最普遍的瓣膜性心脏病是主动脉瓣狭窄(AS),其发病率随着年龄的增长而上升。就目前的原因而言,本文的目的是描述埃及三角洲地区AS患者的临床特征,诊断和治疗策略,以改善这些患者的护理。方法:这项前瞻性、观察性、多中心注册研究纳入了700例人工主动脉瓣患者和轻度、中度和重度AS的临床标准。根据欧洲心脏病学会(ESC)标准,主动脉瓣梯度小于25 mmHg为轻度,25-40 mmHg为中度,大于1 cm2为重度。结果:在年龄方面,男性占43%,女性占57%,严重程度为中度12%,严重程度为18%,4%的参与者接受了人工瓣膜治疗。超声心动图显示41%的患者左室肥厚。射血分数(EF)范围为36 - 70%,心电图68%为窦性心律,18%为房颤,10%为左束支阻滞(BBB), 4%为病理性Q波,治疗类型为药物治疗80%,手术13%,经导管主动脉瓣置换术1%,2%的参与者拒绝手术,4%的参与者医学上不适合手术。结论:目前没有药物治疗能有效地减少AS的发展,患者教育的努力将使50岁及以上人群中AS的发病率激增,无论男女,TAVI和筛查项目都应该在AS患者中启动。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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