Microwave and Induced Thermoacoustic Dual Imaging for Potential Breast Cancer Detection

B. Wang, Ziwen Guo, Zhiqin Zhao, Yifan Chen, Panagiotis KosmasT
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Abstract

Microwave imaging (MWI) and microwave thermoacoustic imaging (MTAI) show great potential for early- stage breast tumor detection. MWI suffers from low spatial resolution for accurate diagnosis, while MTAI is unable to provide quantitative dielectric information and its image quality degrades due to acoustic heterogeneity of breast tissue. To compensate for these drawbacks, we propose a microwave-based dual imaging modality, by combining the conventional MWI and MTAI, for breast tumor detection. First, a low-resolution MWI image will be utilized to provide a rough estimate of the high-dielectric region in breast. Then, the high-dielectric region will be incorporated in MTAI reconstruction to mitigate the acoustic heterogeneity effect. Finally, medical images with ultrasonic resolution and quantitative dielectric information of breast tissue can be ob- tained. We verified this idea by imaging anatomically realistic numerical breast phantoms. Simulation results demonstrate the feasibility of the proposed dual imaging modality by significantly improving the image fidelity and providing quantitative dielectric information.
微波和诱导热声双重成像用于潜在乳腺癌的检测
微波成像(MWI)和微波热声成像(MTAI)在早期乳腺肿瘤检测中显示出巨大的潜力。MWI的空间分辨率较低,无法进行准确诊断,而MTAI无法提供定量的介电信息,并且由于乳腺组织的声学非均匀性,其图像质量下降。为了弥补这些缺点,我们提出了一种基于微波的双重成像模式,结合传统的MWI和MTAI,用于乳腺肿瘤检测。首先,将利用低分辨率MWI图像来提供乳房高介电区域的粗略估计。然后,将高介电区纳入MTAI重建,以减轻声非均质效应。最后,获得具有超声分辨率和乳腺组织定量介电信息的医学图像。我们通过成像解剖学上真实的数字乳房幻影验证了这一想法。仿真结果证明了双成像模式的可行性,显著提高了图像保真度,并提供了定量的介电信息。
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