Magnetic nanotherapeutics of Guerin carcinoma

Abstract

The research of animals with Guerin carcinoma has shown, that magneto-mechano-chemically synthesized magnetic nanocomplex on the basis of Fe3O4 nanoparticles with antitumor anthracycline row antibiotic doxorubicin and next local electromagnetic irradiation by spatially inhomogeneous constant magnetic and variable electromagnetic fields had a greater antitumor effect than conventional doxorubicin and magnetomechano-chemically synthesized magnetic nanocomplex without electromagnetic irradiation.