Früherkennung des Lungenkarzinoms durch CT-Screening - Herausforderungen für die europäische Gesundheitspolitik

W. Schütte, M. Möller
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Abstract

Background: Lung cancer kills more Europeans than any other cancer. In 2013, 269,000 citizens of the EU-28 died from this disease. Lung cancer CT screening has the potential to detect lung cancer at an early stage and improve mortality. All of the randomised controlled trials and cohort low-dose CT (LDCT) screening trials across the world have identified very early stage disease (~70%); the majority of these LDCT trial patients were suitable for surgical interventions and had a good clinical outcome. The 10-year survival in CT screen-detected cancer was shown to be even higher than the 5-year survival for early stage disease in clinical practice at 88%. Methods: Setting up of an EU Commission expert group can be done under Article 168(2) of the Treaty on the Functioning of the European Union, to develop policy and recommendation for Lung cancer CT screening. The Expert Group would undertake: (a) assist the Commission in the drawing up policy documents, including guidelines and recommendations; (b) advise the Commission in the implementation of Union actions on screening and suggest improvements to the measures taken; (c) advise the Commission in the monitoring, evaluation and dissemination of the results of measures taken at Union and national level. Results: This EU Expert Group on lung cancer screening should be set up by the EU Commission to support the implementation and suggest recommendations for the lung cancer screening policy by 2019/2020. Conclusion: Reduce lung cancer in Europe by undertaking a well-organised lung cancer CT screening programme.
通过人体试验对欧洲医疗卫生政策产生筛查效果
背景:欧洲人死于肺癌的人数超过任何其他癌症。2013年,欧盟28国有26.9万公民死于这种疾病。肺癌CT筛查有可能在早期发现肺癌并提高死亡率。全世界所有的随机对照试验和队列低剂量CT (LDCT)筛查试验都发现了非常早期的疾病(约70%);这些LDCT试验患者大多数适合手术干预,临床结果良好。临床实践显示,CT筛查发现的癌症的10年生存率甚至高于早期疾病的5年生存率,为88%。方法:根据《欧盟运作条约》第168(2)条,设立欧盟委员会专家组,制定肺癌CT筛查的政策和建议。专家组将承担:(a)协助委员会拟订政策文件,包括准则和建议;(b)在执行联盟关于筛选的行动方面向委员会提供咨询意见,并建议改进所采取的措施;(c)就监测、评价和传播在联盟和国家一级采取的措施的结果向委员会提供咨询意见。结果:欧盟委员会应成立欧盟肺癌筛查专家组,以支持2019/2020年肺癌筛查政策的实施并提出建议。结论:在欧洲通过组织良好的肺癌CT筛查项目来减少肺癌。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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