Impact of Infection on Glycemic Control in ‎Diabetic Patients; a Hospital-based Cohort ‎Study in Pakistan

Abstract

had poor-control. The mean pre-infection HbA1c in good-control diabetic patients was 6.2% while in poor-control was 8.5% (p: 0.000). While the mean post-infection HbA1c in the good-control was 6.9% and in the poor-control was 8.3% (p: 0.010). The poor-control group had a higher infection-related death rate (62.5% vs. 37.5%, p: 0.72), and multiple sites of infection (65.2% vs. 34.8%, p: 0.47). In the poor-control group, there was a higher rate of re-infection (52.8 vs. 47.2%, p: 0.45), whereas the rate of septic shock was similar (50%, p: 0.42). Conclusion: Based on our study, we conclude that infection had variable effect on glycemic control . Moreover, diabetes per se had a major effect on infection risk, its severity, and mortality, regardless of glycemic control.