STUDY THE PROPHYLACTIC EFFECTS OF MELATONIN AND CYANOCOBALAMIN AGAINST CYCLOPHOSPHAMIDE-INDUCED CARDIOTOXICITY

Waleed K. Ghanim, Muhsin S. G. Al-Moziel, Karamallah Al-Yousof
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Abstract

English Cyclophosphamide chemotherapeutic agent, it's used associated with multiorgan toxicity including the heart. Melatonin and cyanocobalamin possess cardiac-protective properties. This study was designed to evaluate the prophylactic effects of melatonin and cyanocobalamin. Fifty adult male rats have used in the study, divided into five groups each containing ten rats, melatonin
研究褪黑素和氰钴胺对环磷酰胺所致心脏毒性的预防作用
英国环磷酰胺化疗药物,用于治疗包括心脏在内的多器官毒性。褪黑素和氰钴胺素具有保护心脏的特性。本研究旨在评估褪黑素和氰钴胺素的预防作用。在研究中,50只成年雄性大鼠被分成5组,每组含有10只大鼠,使用褪黑素
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