Waleed K. Ghanim, Muhsin S. G. Al-Moziel, Karamallah Al-Yousof
{"title":"STUDY THE PROPHYLACTIC EFFECTS OF MELATONIN AND CYANOCOBALAMIN AGAINST CYCLOPHOSPHAMIDE-INDUCED CARDIOTOXICITY","authors":"Waleed K. Ghanim, Muhsin S. G. Al-Moziel, Karamallah Al-Yousof","doi":"10.21608/bfsa.2022.271771","DOIUrl":null,"url":null,"abstract":"English Cyclophosphamide chemotherapeutic agent, it's used associated with multiorgan toxicity including the heart. Melatonin and cyanocobalamin possess cardiac-protective properties. This study was designed to evaluate the prophylactic effects of melatonin and cyanocobalamin. Fifty adult male rats have used in the study, divided into five groups each containing ten rats, melatonin","PeriodicalId":345040,"journal":{"name":"Bulletin of Pharmaceutical Sciences. Assiut","volume":"34 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Bulletin of Pharmaceutical Sciences. Assiut","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.21608/bfsa.2022.271771","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
English Cyclophosphamide chemotherapeutic agent, it's used associated with multiorgan toxicity including the heart. Melatonin and cyanocobalamin possess cardiac-protective properties. This study was designed to evaluate the prophylactic effects of melatonin and cyanocobalamin. Fifty adult male rats have used in the study, divided into five groups each containing ten rats, melatonin