Antisense oligonucleotides targeting microRNA binding sites in the GRN mRNA increase progranulin translation: potential therapeutic strategy for frontotemporal dementia

ASPET 2023 Annual Meeting Abstract - Central Nervous System Pharmacology - Neuropharmacology Pub Date : 2023-05-18 DOI:10.1124/jpet.122.246730

Sp Jones, Geetika Aggarwal, Yousri Benchaar, J. Bélanger, Myriam Sévigny, Denise M. Smith, M. Niehoff, I. M. D. Vera, T. Petkau, B. Leavitt, K. Ling, P. Jafar-Nejad, F. Rigo, J. Morley, A. Nguyen

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针对GRN mRNA中microRNA结合位点的反义寡核苷酸增加颗粒前蛋白翻译:额颞叶痴呆的潜在治疗策略

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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ASPET 2023 Annual Meeting Abstract - Central Nervous System Pharmacology - Neuropharmacology

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