Experimental study of RoboRat through deep brain stimulation and carbon nanotube coated microelectrodes

V. Azimirad, P. Shahabi, Soheil Jafarizade, Taraneh Dehghan Helan, J. Mahmoudi
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Abstract

This paper presents a new test bed for control of RoboRat through deep brain stimulation. Alive free rat is controlled in order to move in desired directions. Surgery is performed on a rat's brain to put microelectrodes in MFB and S1BF areas (in left and right hemispheres). We used four bipolar implanted microelectrodes which are CNT coated by drop coating method. In experiments, the exact locations of electrodes are tested by removing the brain. Electrical stimulation of rat is done through an isolated portable signal generator circuit (as slave) which is carried by the rat. It has a RF receiver for communication with computer and a microcontroller for signal generation. Stimulation electrodes are connected to microcontroller so that the resistant is about 100 KΩ in artificial cerebral spinal fluid. Slave system is connected wirelessly to a computer (as master) so that an operator is able to control it. A graphic user interface is designed for ease of operation. The remote control system is implemented and tested on rat. The stimulation of both hemispheres is done simultaneously and non-simultaneously. The whole system is examined in three-day period and it showed that the brain-computer interface for rat using CNT coated microelectrodes is the effective in practice.
脑深部电刺激与碳纳米管微电极的实验研究
本文提出了一种新的机器人脑深部刺激控制实验平台。控制活的自由鼠,使其向指定的方向移动。在大鼠的大脑上进行手术,将微电极放置在MFB和S1BF区域(在左右半球)。我们使用了四个双极植入微电极,这些微电极是用碳纳米管滴涂法涂覆的。在实验中,电极的确切位置是通过移除大脑来测试的。对大鼠的电刺激是通过一个孤立的便携式信号发生器电路(作为从电路)完成的,该电路由大鼠携带。它有一个用于与计算机通信的射频接收器和一个用于信号产生的微控制器。将刺激电极连接到微控制器上,使人工脑脊液的电阻约为100 KΩ。从系统以无线方式连接到计算机(作为主系统),以便操作人员能够控制它。图形用户界面设计便于操作。远程控制系统在大鼠身上进行了实现和测试。对两个大脑半球的刺激可以同时进行,也可以不同时进行。对整个系统进行了为期三天的测试,结果表明碳纳米管包覆微电极的脑机接口在实际应用中是有效的。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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