N. Krstajić, R. Walker, J. Levitt, S. Poland, Day-Uei Li, S. Ameer-Beg, R. Henderson
{"title":"A 256 × 8 SPAD line sensor for time resolved fluorescence and raman sensing","authors":"N. Krstajić, R. Walker, J. Levitt, S. Poland, Day-Uei Li, S. Ameer-Beg, R. Henderson","doi":"10.1109/ESSCIRC.2014.6942042","DOIUrl":null,"url":null,"abstract":"A 256 × 8 single photon avalanche diode (SPAD) time-resolved single photon counting (TCPSC) line sensor enables both fluorescence and Raman spectroscopy in a single device. The 23.78μm pitch, 46.8% fill-factor SPAD array is implemented in a 0.13μm CMOS image sensor process. Integrating time to digital converters (TDCs) implement on-chip mono-exponential fluorescence lifetime pre-calculation allowing timing of 65k photons/pixel at 500s-1 line rate at 40ps resolution using centre-of-mass method (CMM). TCSPC histograms may also be generated with 320ps bin resolution for multi-exponential analysis.","PeriodicalId":202377,"journal":{"name":"ESSCIRC 2014 - 40th European Solid State Circuits Conference (ESSCIRC)","volume":"31 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2014-11-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"7","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"ESSCIRC 2014 - 40th European Solid State Circuits Conference (ESSCIRC)","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1109/ESSCIRC.2014.6942042","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 7
Abstract
A 256 × 8 single photon avalanche diode (SPAD) time-resolved single photon counting (TCPSC) line sensor enables both fluorescence and Raman spectroscopy in a single device. The 23.78μm pitch, 46.8% fill-factor SPAD array is implemented in a 0.13μm CMOS image sensor process. Integrating time to digital converters (TDCs) implement on-chip mono-exponential fluorescence lifetime pre-calculation allowing timing of 65k photons/pixel at 500s-1 line rate at 40ps resolution using centre-of-mass method (CMM). TCSPC histograms may also be generated with 320ps bin resolution for multi-exponential analysis.