Anti-Diabetic Plants Used in Cameroon with a Potential of Endogenous Renewal Pancreatic ß-Cells Important in the Management of Diabetes

Abstract

Diabetes is a chronic metabolic, genetic and environmental worldwide disease characterized by hyperglycemia. This high blood glucose concentration is due to insufficient synthesis of endogenous insulin by the pancreas beta cells for the type-1 diabetes, or impaired insulin production and/or activity for type-2 diabetes [1]. So type-1 diabetes is an autoimmune disease due to the destruction of T-cell mediated located in the pancreas beta cells. Yet type-2 diabetes is characterized by a development of insulin resistance and beta cell dysfunction. These two metabolic disorders are strongly associated with obesity and a sedentary lifestyle [2,3]. In many developing countries diabetes was considered as a disease of wealth countries. That is why three decades ago, undiagnosed diabetic patients perished, killed by this insipid and complicated pathology [4,5]. Face to this undesirable situation many scientific, administrative and social efforts were done in Cameroon to combat diabetes. The recrudescence of the prevalence of diabetes, especially amongst towns’ dwellers, the over expensive cost and the long duration of treatment oblige Cameroonians through local therapists to utilize medicinal plants to fight this symptomatic disease. The plants used were selected amongst medicinal plants which were used from centuries for the treatment of various human ailments. Herbal preparations because of its cost effective, safety and substitution for the treatment of diseases are also strongly used for diabetes mellitus [6]. The purpose of the present article is to identify from medicinal plants published by Cameroonians those which Crimson Publishers Wings to the Research Research Article