Antimicrobial Effects of Essential Oils on Pseudomonas Aeruginosa

Qinya Yi, Jilun Zhang, Dityuk Ai
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Abstract

Pseudomonas aeruginosa is a nosocomial pathogen that often develops multidrug resistance. Treating P. aeruginosa infection can be difficult, high cost with high mortality rate. Novel treatment is needed to handle this common clinically encountered issue. Recent research has suggested that Essential Oils (EOs) have the potential to act as antibiotics on P. aeruginosa by inhibiting the formation of biofilms and the functions of efflux pumps. Because of lower cost, EOs have huge potential for developing countries and underdeveloped area. Innovative therapeutic technologies, such as nano-encapsulation of EOs, have been utilized to enhance EOs’ effectiveness. This review summarizes the mechanisms of EOs in P. aeruginosa treatments, the current application of EOs, and future developments of EOs in and beyond clinical practice.
精油对铜绿假单胞菌的抑菌作用
铜绿假单胞菌是一种经常产生多药耐药的医院病原菌。治疗铜绿假单胞菌感染可能是困难的,高成本和高死亡率。需要新的治疗方法来处理这一常见的临床问题。最近的研究表明,精油(EOs)有可能通过抑制生物膜的形成和外排泵的功能而作为铜绿假单胞菌的抗生素。由于成本较低,EOs在发展中国家和欠发达地区具有巨大的潜力。创新的治疗技术,如EOs的纳米封装,已被用于提高EOs的有效性。本文综述了EOs在铜绿假单胞菌治疗中的作用机制、EOs的应用现状以及EOs在临床内外的未来发展。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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