Hba1c: Point of Care Testing in Control of Type-2 Diabetes Mellitus in Population of Nowshera

Hamzulla Khan, M. B. Khan, S. Hussain, S. Zahoor, Muhammad Asif, Shahtaj Khan
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Abstract

Background: Diabetes mellitus is a highly prevalent non-communicable disease with a further implication of the development of life-threatening diseases like cardiovascular disease and stroke. Objectives: To determine the glycosylated hemoglobin levels utility in assessing the point of care testing in the control of diabetes mellitus in the population of Nowshera in a hospital-based study. Methods: This was a cross-sectional study, conducted in the department of Pathology in collaboration with the Department of General Medicine, Qazi Hussain Ahmed Medical Complex, Nowshera, from February 2019 to January 2020. Descriptive statistic was used for describing the variables. A Chi-square test was used for the association of Hba1c in gender groups. SPSS version 25 was used for data analysis. Results: Out of the total 119 patients, 44 (37%) were males and 75(63%) were females. The mean age with standard deviation was 53±9.5. The Mean Hba1c with standard deviation was 10.53± 2.38. Sixty-eight (57.1%) of the patients were in the age range 46-60 years. Eighty-eight (73.9%) were poorly controlled diabetics with Hba1c of >9%. Using the chi-square test it was observed that gender has no significant impact on the severity of the disease (p= 0.38). The relative risk of female gender and for age >50years was (RR=1.11). Conclusion: We observed that the majority of the patients had poorly controlled diabetes with Hba1c >9% which is an alarming situation. Age and gender play a very important role in the prognosis of diabetes mellitus.
Hba1c:护理点检测在Nowshera人群控制2型糖尿病中的作用
背景:糖尿病是一种高度流行的非传染性疾病,进一步暗示了心血管疾病和中风等危及生命的疾病的发展。目的:在一项以医院为基础的研究中,确定糖化血红蛋白水平在评估诺谢拉人群糖尿病控制的护理点试验中的效用。方法:这是一项横断面研究,于2019年2月至2020年1月在病理学系与诺谢拉Qazi Hussain Ahmed医疗综合体普通医学部合作进行。采用描述性统计对变量进行描述。Hba1c在不同性别间的相关性采用卡方检验。采用SPSS 25版本进行数据分析。结果:119例患者中,男性44例(37%),女性75例(63%)。平均年龄,标准差为53±9.5。平均糖化血红蛋白(Hba1c)为10.53±2.38。68例(57.1%)患者年龄在46 ~ 60岁之间。88例(73.9%)糖尿病控制不良,Hba1c >9%。使用卡方检验观察到,性别对疾病的严重程度没有显著影响(p= 0.38)。女性和年龄>50岁的相对危险度为(RR=1.11)。结论:我们观察到大多数患者控制不良,Hba1c >9%,这是一个令人担忧的情况。年龄和性别是影响糖尿病预后的重要因素。
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