NONALCOHOLIC FATTY LIVER DISEASE AND ALBUMINURIA : A SYSTEMATIC REVIEW

Devita Nur Amelia
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Abstract

Background: The presence of fat storage in the liver that is larger than 5% of the liver's weight is diagnostic of nonalcoholic fatty liver disease (NAFLD), which can occur in the absence of excessive alcohol consumption or a secondary cause of liver illnesses. It is interesting to note that it has been hypothesised that NAFLD might be able to contribute to albuminuria by exacerbating the endothelial dysfunction that results from systemic inflammation. Aim: This article examines the link between nonalcoholic fatty liver disease and albuminuria. Methods: This study showed that it met all of the requirements by looking at the Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) 2020 guidelines. So, the experts could make sure that the study was as current as possible. The search method used a number of electronic reference databases, such as Pubmed and SagePub, to look for papers that were published between 2000 and 2023. We didn't look at review papers, articles that had already been published, or articles that were only half done. Result: In the PubMed database, the results of our search brought up 89  articles, whereas the results of our search on SagePub brought up 33 articles. The results of the search conducted for the last year of 2013 yielded a total of 22 articles for PubMed and 16 articles for SagePub. In the end, we compiled a total of 17 papers, 12 of which came from PubMed and five of which came from SagePub. We included seven research that met the criteria. Conclusion: Study has consistently shown that there is a correlation between NAFLD and albuminuria.
非酒精性脂肪肝和蛋白尿:系统综述
背景:肝脏脂肪储存大于肝脏重量的5%是非酒精性脂肪性肝病(NAFLD)的诊断,这可能发生在没有过量饮酒或肝脏疾病的继发原因的情况下。值得注意的是,有假设认为NAFLD可能通过加剧全身炎症导致的内皮功能障碍而导致蛋白尿。目的:本文探讨非酒精性脂肪性肝病与蛋白尿之间的关系。方法:本研究显示,通过查看系统评价和荟萃分析(PRISMA) 2020指南的首选报告项目,它满足了所有要求。因此,专家们可以确保这项研究尽可能是最新的。搜索方法使用了许多电子参考数据库,如Pubmed和SagePub,来查找2000年至2023年之间发表的论文。我们没有看评论论文,已经发表的文章,或者只做了一半的文章。结果:在PubMed数据库中,我们搜索的结果是89篇文章,而在SagePub上搜索的结果是33篇文章。2013年最后一年的搜索结果显示,PubMed总共有22篇文章,SagePub有16篇文章。最后,我们一共编辑了17篇论文,其中12篇来自PubMed, 5篇来自SagePub。我们纳入了7项符合标准的研究。结论:研究一致表明NAFLD与蛋白尿之间存在相关性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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