Clinico Pathological Review of Adnexal Masses in Children and Adolescents at a University Hospital

T. Malik, A. Aziz, U. Chishti, Mohammed Arif Mateen Khan
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Abstract

Background & Objective: The study objective was to review the clinic-pathological characteristics of adnexal masses in the children and adolescent population in our institution. Methods: Retrospective analysis of 178 adolescent patients including neonates, presenting with adnexal masses between January 2000-December 2012, was performed. Results: Records of a total of 178 patients were analyzed. The mean age was 14 years. The most common symptom was abdominal pain noted in 146(82%) patients followed by nausea and vomiting in 28(15.7%) and incidental findings in 19(10.7%). The majority of the ovarian masses were benign. The follicular cyst was the most common histopathological type in 66 patients (37.1%) followed by a hemorrhagic cyst in 40(22.5%), benign teratoma in 21(11.8%), benign serous cyst in 20 patients (11.2%), endometrioma and mucinous cystadenoma in 13 patients (7.3%). The average tumor size observed in the present study was 7.84cms. However, the size varied in different age groups such as 4.27 cm size in neonates, and 7.1 cm in 1-14 years age group, and 8.61 cm in 15-19 years age group with a P-value of 0.009. Out of a total of 178 patients, 46(25.8%) were managed conservatively. However, 90(50.6%) patients underwent ovarian cystectomy, 26(14.6%) were managed by unilateral salpingo-oophorectomy, 10(5.6%) by unilateral oophorectomy. Aspiration and biopsy were done in 6(3.4%) patients. Conclusion: Incidence of adnexal masses increases with age with maximum cases between age 14 and above. Adolescent girls with adnexal masses can have variable presentations however abdominal pain is the most common symptom. Mostly these are benign masses therefore conservative approach for treatment should be adopted.
某大学附属医院儿童及青少年附件肿块的临床病理分析
背景与目的:研究目的是回顾我院儿童和青少年人群中附件肿块的临床病理特征。方法:回顾性分析2000年1月至2012年12月期间出现附件肿块的178例青少年患者(包括新生儿)。结果:共分析178例患者的记录。平均年龄为14岁。最常见的症状是146例(82%)患者出现腹痛,其次是28例(15.7%)恶心和呕吐,19例(10.7%)出现意外症状。卵巢肿块多数为良性。66例(37.1%)以滤泡性囊肿最常见,其次为出血性囊肿40例(22.5%),良性畸胎瘤21例(11.8%),良性浆液性囊肿20例(11.2%),子宫内膜异位瘤和粘液性囊腺瘤13例(7.3%)。本研究中观察到的肿瘤平均大小为7.84cm。但不同年龄组的尺寸差异较大,新生儿尺寸为4.27 cm, 1-14岁为7.1 cm, 15-19岁为8.61 cm, p值为0.009。178例患者中,46例(25.8%)采用保守治疗。其中90例(50.6%)行卵巢囊肿切除术,26例(14.6%)行单侧输卵管卵巢切除术,10例(5.6%)行单侧卵巢切除术。6例(3.4%)患者行抽吸和活检。结论:附件肿块的发病率随年龄增长而增加,以14岁及以上为最多。青春期女孩的附件肿块可以有不同的表现,但腹痛是最常见的症状。多数为良性肿块,应采取保守治疗。
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