Tracking the diversity and Mediterranean lineage of Brucella melitensis isolates from different animal species in Turkey using MLVA-16 genotyping

IF 1.5

German Journal of Veterinary Research Pub Date : 2022-05-01 DOI:10.51585/gjvr.2022.1.0037

Kadir Akar, Farah Tatar, G. Schmoock, G. Wareth, H. Neubauer, O. Erganis

{"title":"Tracking the diversity and Mediterranean lineage of Brucella melitensis isolates from different animal species in Turkey using MLVA-16 genotyping","authors":"Kadir Akar, Farah Tatar, G. Schmoock, G. Wareth, H. Neubauer, O. Erganis","doi":"10.51585/gjvr.2022.1.0037","DOIUrl":null,"url":null,"abstract":"Brucellosis is a zoonotic disease with a high prevalence in humans and farm animals in Turkey. However, data on the genetic diversity of Brucella spp. circulating in Turkey and parts of the Mediterranean region are limited. In the present study, the genetic diversity of 50 B. melitensis isolates from seven regions of Turkey was investigated using multi-locus variable number tandem repeats analysis (MLVA-16). The profiles were compared with 163 B. melitensis isolates recovered from the Mediterranean basin. B. melitensis strains from Turkey contain 46 different genotypes and consist of two main clusters. B. melitensis isolates from Turkey were closely related to isolates from Greece and some Portuguese strains. The same genotypes isolated from different sites show the spread between sites. Therefore, uncontrolled animal movements and the trade of imported animals can be important factors for the spread of brucellosis. The endemic occurrence of B. melitensis in the Mediterranean basin is a result of socio-historical links between Mediterranean countries. Turkish strains belong to the Eastern Mediterranean line. Eradicating brucellosis in countries of the Mediterranean basin with high prevalence is a demanding need to reduce trade barriers and, more importantly, prevent human suffering","PeriodicalId":310978,"journal":{"name":"German Journal of Veterinary Research","volume":"32 1","pages":"0"},"PeriodicalIF":1.5000,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"4","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"German Journal of Veterinary Research","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.51585/gjvr.2022.1.0037","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}

引用次数: 4

Abstract

Brucellosis is a zoonotic disease with a high prevalence in humans and farm animals in Turkey. However, data on the genetic diversity of Brucella spp. circulating in Turkey and parts of the Mediterranean region are limited. In the present study, the genetic diversity of 50 B. melitensis isolates from seven regions of Turkey was investigated using multi-locus variable number tandem repeats analysis (MLVA-16). The profiles were compared with 163 B. melitensis isolates recovered from the Mediterranean basin. B. melitensis strains from Turkey contain 46 different genotypes and consist of two main clusters. B. melitensis isolates from Turkey were closely related to isolates from Greece and some Portuguese strains. The same genotypes isolated from different sites show the spread between sites. Therefore, uncontrolled animal movements and the trade of imported animals can be important factors for the spread of brucellosis. The endemic occurrence of B. melitensis in the Mediterranean basin is a result of socio-historical links between Mediterranean countries. Turkish strains belong to the Eastern Mediterranean line. Eradicating brucellosis in countries of the Mediterranean basin with high prevalence is a demanding need to reduce trade barriers and, more importantly, prevent human suffering

查看原文本刊更多论文

利用MLVA-16基因分型技术追踪土耳其不同动物种分离的梅利特布鲁氏菌的多样性和地中海谱系

布鲁氏菌病是一种人畜共患疾病，在土耳其的人类和农场动物中流行率很高。然而，关于在土耳其和地中海部分地区流行的布鲁氏菌属遗传多样性的数据有限。本研究采用多位点可变数串联重复序列分析(MLVA-16)对土耳其7个地区50株melitensis分离株的遗传多样性进行了研究。并与从地中海盆地分离的163株melitensis菌株进行了比较。来自土耳其的melitensis菌株包含46种不同的基因型，由两个主要集群组成。土耳其分离株与希腊分离株和部分葡萄牙分离株亲缘关系密切。从不同位点分离的相同基因型显示出位点间的传播。因此，不受控制的动物运动和进口动物贸易可能是布鲁氏菌病传播的重要因素。在地中海盆地发生的羊腹螺旋藻地方性流行是地中海国家之间社会历史联系的结果。土耳其菌株属于东地中海线。在地中海盆地高流行国家根除布鲁氏菌病是减少贸易壁垒，更重要的是防止人类痛苦的迫切需要

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

German Journal of Veterinary Research

CiteScore

2.40

自引率

0.00%

发文量