Specific Anti-Obese Synbiotics to Suit Genetically Different Obese Persons

M. Haridas, A. Sabu
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Abstract

Ayurvedic fermentation as prescribed in classical texts is a versatile and powerful protocol for developing novel, traditional-like medicines. Ayurvedic medication, having a Prakriti (genetic) determinant, needs to be considered suitable for addressing metabolic disorders with immunologic implications, influenced by gut microbiome (as evidenced by the enterotypes). Obesity is a pathologic state on which the gut microbiota exercises influence in inflammatory and metabolic ways. When coupled with reverse pharmacology it would yield highly predictable results. It also bears potentials for redefining the protocol itself to deliver future products. In this article we essay on conceptualising the production and the prospect of developing new anti-obesity fermented nutraceutics/synbiotics to suit the prakriti of obese persons by prakriti-specific gut microbiome.
特殊的抗肥胖合成药物,以适应基因不同的肥胖者
经典文献中规定的阿育吠陀发酵是开发新型传统药物的多功能和强大的协议。阿育吠陀药物具有Prakriti(遗传)决定因素,需要被认为适合于解决受肠道微生物群影响的具有免疫学意义的代谢紊乱(如肠道型所证明的)。肥胖是肠道菌群以炎症和代谢方式影响的一种病理状态。当与反向药理学相结合时,它将产生高度可预测的结果。它还具有重新定义协议本身以提供未来产品的潜力。本文就利用肥胖特异性肠道微生物群开发适合肥胖人群的新型抗肥胖发酵营养品/合成制剂的概念、生产和前景进行了综述。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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