Phytochemical Analysis and Anthelmintic Activity of Phyllanthus Emblica Linn

A. Yadav, Manisha Chandrakar, R. Devi, Aakanchha Singh, Varsha Sahu, Khomendra Kumar Sarwa, Dron Kumar Sahu
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Abstract

Phyllanthus emblica is a deciduous shrub used in the Ayurvedic medicinesystem and has been reported to boost defense against ailments. The different parts of these plants are used to manage a large number of health conditions such as liver disease, heart disease, ulcers, anemia, humanoids, and other diseases. The ethanolic leaf extract of Phyllanthus emblica was evaluatedfor its anthelmintic activity against the Pheretima posthuman(Indian adult earthworm).The fresh leafextract of thesewith different concentrations (30 mg/ml, 60 mg/ml, and, 100 mg/ml) was tested in invitro, to investigate the paralysis and death times of worms.The ethanolic extract showed concentration-dependent anthelmintic activity at all doses. Normal saline served as the control group while albendazole (20 mg/ml) served as the reference medication. The Ethanolic Leaf Extract of Phyllanthus emblica was found to possess vermifuge (paralysis) and vermicidal (death) activity at all dose levels.
余甘子植物化学分析及驱虫活性研究
余甘子是阿育吠陀医学系统中使用的一种落叶灌木,据报道可以增强对疾病的防御。这些植物的不同部分被用来管理大量的健康状况,如肝病、心脏病、溃疡、贫血、类人疾病和其他疾病。研究了余甘子叶乙醇提取物对印度成年蚯蚓的驱虫活性。以不同浓度(30 mg/ml、60 mg/ml和100 mg/ml)的鲜叶提取物进行体外实验,研究其对蠕虫麻痹和死亡时间的影响。乙醇提取物在所有剂量下均表现出浓度依赖性的驱虫药活性。生理盐水为对照组,阿苯达唑(20mg /ml)为参比药物。在所有剂量水平下,甘油三酯乙醇叶提取物均具有驱虫(麻痹)和杀虫(死亡)活性。
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