Effect of Psychological Intervention on Perioperative Prognosis of Adult Orthotopic Liver Transplantation

Abstract

Objective: Psychological intervention was carried out on depression and anxiety of liver transplantation patients to evaluate the inflammation level of patients before and after operation. Then analyze the role of psychological intervention in the perioperative prognosis of liver transplantation. Methods: 27 patients with liver transplantation included in the study were randomly divided into control group (n=14) and intervention group (n=13). Psychological intervention was carried out in the intervention group from 3 days before operation until 3 days after operation. The anxiety and depression of patients in the intervention group and the control group were evaluated with Beck Anxiety Inventory (BAI) and Beck Depression Inventory (BDI) before and after operation, and the relevant data were collected for statistical analysis. Results: There was no significant statistical difference in the preoperative demographic data (P > 0.05). The inflammatory indicators with statistical differences after operation were ALT (p=0.010), AST (p=0.003), GGT/ALT (p=0.011), PCT (p=0.032). The median BAI of the control group and the intervention group were 26 and 27 respectively, and the median BDI were 3.5 and 4 respectively. There was no significant difference in the levels of BAI (p=0.618) and BDI (p=0.804); after operation, the median BAI of the control group and the intervention group were 27 and 24, and the median BDI were 3 and 1, respectively. The levels of BAI (p=0.004) and BDI (p=0.028) showed significant differences. Conclusions: Psychological intervention may affect the postoperative inflammation level of patients by improving their depression and anxiety to some extent. However, the impact on postoperative quality of life and long-term prognosis remains to be further evaluated.