LAMBDA CYHALOTHRIN INDUCED OXIDATIVE STRESS ON BRAIN TISSUES OF RATTUS NORVEGICUS AND ITS AMELIORATION BY GREEN TEA EXTRACT

E. Yadav, Vivek Kumar, Harendra Nath Sharma
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Abstract

Lambda cyhalothrin is one of the most important agricultural pesticides extensively used around the world. Pyrethroids are specially recommended insecticides as they have low mammalian toxicity, but they are known to cause an alteration in biochemical parameters and affect the oxidative status of the body through producing free radicals. However, it has been found that some herbal extracts can ameliorate the toxicity induced by the pesticides and other chemicals but the search for such compounds will always be an urgent need to achieve the optimum degree of amelioration. For this purpose, the present study was designed to evaluate the oxidative stress produced by lambda cyhalothrin, a synthetic type-II pyrethroid and ameliorating effect of green tea extract in albino rats.
氯氟氰菊酯诱导褐家鼠脑组织氧化应激及绿茶提取物的改善作用
氯氟氰菊酯是世界上广泛使用的重要农药之一。拟除虫菊酯是特别推荐的杀虫剂,因为它们对哺乳动物的毒性较低,但已知它们会引起生化参数的改变,并通过产生自由基影响身体的氧化状态。然而,已经发现一些草药提取物可以改善农药和其他化学物质引起的毒性,但寻找这样的化合物将永远是迫切需要的,以达到最佳程度的改善。为此,本研究旨在评价合成ii型拟除虫菊酯氰氯氰菊酯对白化病大鼠的氧化应激及绿茶提取物的改善作用。
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