[Topical differences in estrogen receptor content of primary breast cancer].

Abstract

In 50 primary cancers of the mammary gland, tissue samples from three different parts of each tumor were analyzed for estrogen content by agar gel electrophoresis. In 12 tumors receptor-rich and receptor-poor zones were detected within the tumor for the 4-s fraction, and in 11 tumors for the 8-s fraction. Confidence limits (99%) indicate that these findings might range from 10.4% to 42.5% for the 4-s fraction, and 10.2%-44.1% for the 8-s fraction.