Limitation of Jalauka (medicinal leech) application in the prevention of recurrence of keloid: A case report

Snehal Sonani, Pragati Patel, T. Dudhamal
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Abstract

Keloid can be defined as a benign dermal fibroproliferative disorder with no malignant potential. The keloids tend to occur following trivial physical trauma in genetically predisposed individuals. Jalauka (medicinal leech, Hirudo medicinalis) is famed to use in all skin disorders caused by vitiation of Rakta (~blood) and Pitta Dosha (a functional regulatory factor of the body). Many studies also have claimed that the saliva of medicinal leeches potentiates wound healing. It helps in healthy scar formation by inhibiting the conversion of fibrinogen to fibrin. Therefore, a hypothesis was made that medicinal leech application can be helpful in the healing of the wound without keloid formation in patients with keloid formation tendencies. In the present study, case of a 38-year-old male patient infected sebaceous cyst at the right upper back (scapular region) with a previous history of keloid formation after surgical scar was treated by weekly medicinal leech application five times after excision of the cyst under local anesthesia. Initiation wound healing was normal in the studied case until complete epithelization. After 2 months of complete healing, gradual hardening and shiny appearance with irregular margin became very prominent and seemed to convert in keloid, although other associated symptoms were absent. The findings of this case report indicate the limited effect of the medicinal leech application and the requirement of a multimodel therapeutic approach for healthy wound healing in keloid tendency patients.
药用水蛭在预防瘢痕疙瘩复发中的局限性1例
瘢痕疙瘩是一种良性皮肤纤维增生性疾病,无恶性潜能。在遗传易感的个体中,瘢痕疙瘩往往发生在轻微的身体创伤之后。Jalauka(药用水蛭,Hirudo medicinalis)因Rakta(~血液)和Pitta Dosha(身体的功能调节因子)的破坏而引起的所有皮肤疾病而闻名。许多研究也声称药用水蛭的唾液能促进伤口愈合。它通过抑制纤维蛋白原向纤维蛋白的转化来帮助健康疤痕的形成。因此,我们假设药蛭的应用可以帮助有瘢痕疙瘩形成倾向的患者愈合无瘢痕疙瘩的伤口。本研究报告一例38岁男性患者,其右侧上背部(肩胛骨区)皮脂腺囊肿感染,既往有手术瘢痕后瘢痕形成史,在局部麻醉下切除囊肿后,每周应用药蛭5次治疗。在研究的病例中,初始伤口愈合正常,直到上皮完全形成。完全愈合2个月后,逐渐硬化和有光泽的外观,边缘不规则变得非常突出,似乎转化为瘢痕疙瘩,尽管没有其他相关症状。本病例报告的研究结果表明,药蛭应用的效果有限,需要多模式治疗方法来促进瘢痕疙瘩倾向患者的健康伤口愈合。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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