DEVELOPMENT AND IN VITRO EVALUATION OF RED RASPBERRY FRUIT EXTRACT O/W COSMETIC EMULGEL

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Abstract

Background and objective: The object of this study was to develop a stable O/W (oil-in-water) cosmetic emulgel of red raspberry fruit extract and its in vitro evaluation.Methodology: A base with no plant extract and a formulation with 4% extract of red raspberry were prepared and kept at different storage conditions in stability chambers i.e., 8, 25, and 40 °C, and 40 °C ±75% RH for a period of 12 weeks. Stability parameters i.e. color, phase separation, liquefaction, pH and electrical conductivity tests were performed at interval of 0, 24, 48, 72h and 7, 14, 21, 28, 45, 60, 75 and 90 days.Results: The results showed that there were unchanged organoleptic properties in terms of appearance, color and odor, unchanged properties after centrifugation and phase separation, and in terms of electrical conductivity and liquefaction. Significant change in pH of base and active formulation were observed with the passage of time.Conclusion: As a conclusion of this work a stable topical formulation of O/W emulgel carrying red raspberry fruit extract can be formulated and can be used for cosmetic purposes.
红树莓果提取物o / w化妆品凝胶的研制及体外评价
背景与目的:本研究的目的是研制一种稳定的红覆盆子提取物O/W(水包油)化妆品凝胶并对其进行体外评价。方法:制备不含植物提取物的基质和含4%红树莓提取物的配方,分别在8℃、25℃、40℃和40℃±75% RH的稳定箱中保存12周。在0、24、48、72h和7、14、21、28、45、60、75和90天的间隔时间内进行稳定性参数,即颜色、相分离、液化、pH和电导率测试。结果:结果表明,其外观、颜色、气味、离心、相分离、电导率、液化等感官特性均无变化。随着时间的推移,碱和活性配方的pH值发生了显著变化。结论:制备了一种稳定的红覆盆子提取物O/W乳状液外用配方,可用于化妆品。
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