Safety and Efficacy of Paracetamol + Lignocaine Injection in Patients with High-grade Fever: A Prospective Analysis

Abstract

High-grade fever is a common presenting symptom in various infectious and inflammatory conditions, requiring prompt and effective management. Paracetamol (acetaminophen) is a widely used antipyretic agent, while lignocaine possesses analgesic and anti-inflammatory properties. This prospective study evaluated and established the safety and efficacy of paracetamol + lignocaine injection in patients with high-grade fever. The study outcomes revealed that after administering paracetamol and lignocaine injections, 89% of patients experienced a reduction in high fever, while 68.6% of patients reported no or mild pain at the injection site. Based on these findings, the authors recommend that health care professionals consider the potential benefits of using paracetamol and lignocaine injections for patients suffering from severe fever accompanied by pain and discomfort.