Comparison of Remineralization Effect of Casein Phosphopeptide Amorphous Calcium Phosphate and Sodium Fluoride on Enamel Surface after Orthodontic Debonding: An In vitro study

Abstract

OBJECTIVE: To compare the result of "casein phosphopeptide amorphous calcium phosphate" with "sodium fluoride" (900 ppm) in remineralization of enamel after orthodontic debonding. METHODOLOY: This study was performed on premolars. Teeth were distributed into 3 groups A, B and C. The baseline microhardness of samples was measured. To create artificial demineralization, all samples were dipped in demineralizing solution. Surface microhardness (SMH) was re-measured for demineralization. Then, CPP-ACP was applied on teeth of gp B and NaF (900 ppm) was applied on teeth of gp C for remineralization. All teeth were cycled between deionized water and surface treatment for 12 weeks. The SMH of gp B and gp C was re-measured for remineralization. Paired t-test and Independent t-test were practiced to match MH before and after demineralization while keeping P value < 0.05. One way ANOVA was practiced to match mean difference in baseline MH and after demineralization. RESULTS: The baseline SMH of enamel decrease after demineralization. After application of test materials, mean SMH increased by 230.2 VHN and 207.5 VHN respectively. The %age of SMHR reveal the recovery rate of 41.2% in CPP-ACP and 19.1% in NaF group. CONCLUSION: For treating post orthodontic demineralized lesions, a remineralizing cream having casein phosphopeptide stabilized amorphous calcium phosphate is useful with some mineral and aesthetic improvements. KEYWORDS: Casein Phosphopeptide Amorphous Calcium Phosphate (CPP-ACP), Sodium Fluoride (NaF), Surface Microhardness (SMH), Vickers Hardness Number (VHN), Rmineralization.