Identification of markers of acute inflammatory process in the pulmonary tuberculosis

Abstract

Tuberculosis remains, according to the WHO report, one of the global problems in the world, especially in the form caused by drug-resistant mycobacteria. The identification of special biochemical markers allowing to assess the necessity of surgery or therapy prolongation remains a challenge. We consider promising markers – metalloproteinases – analyzing statistics of data obtained from patients with pulmonary tuberculosis forced by different strains of Mycobacterium tuberculosis. The discussed results could be used for further development of a precise biochemical data-based diagnostic and prognostic tool.