Retinal Fundus Image Classification Using Hybrid Deep Learning Model

Shobhana Lakhera, Amit Garg
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Abstract

Diabetic retinopathy (DR) is a disease related with diabetes. DR causes lesions on the eye retina that can affect the human vision. DR needs to be detected at its earlier stage, otherwise in the worst situation patients suffer from DR may lead to blindness. Currently, DR is diagnosed using fundus images of the retina using manual methods by medical practitioners. Automated methods are more reliable, cost-effective, and time savers as compared to their manual counterpart. In this work, a deep learning (DL) model is proposed to automatically recognize DR images by classifying retinal fundus images into five different classes. A hybrid DL model of three different DL pretrained models AlexNet, VGGNet, and ResNet-18 is used. Then the performance of the combined proposed model is enhanced using the AdaBoost algorithm. AdaBoost algorithm is used to exploit dependency among different DL models. It can handle missing values and outliers. The APTOS and Messidor-2 dataset are used for the training of all pre-trained models and proposed model. Then performance of the proposed hybrid DL model along with three other pretrained DL models is evaluated based on performance metrics accuracy, sensitivity, specificity, and F1score. From the obtained results it is to be noted that performance metric values for the proposed hybrid model are at higher side as compared to the other pretrained DL models. Hence, the proposed method is a potential method for the DR image classification.
基于混合深度学习模型的视网膜眼底图像分类
糖尿病视网膜病变(DR)是一种与糖尿病相关的疾病。DR会对视网膜造成损害,从而影响人类的视力。DR需要在早期发现,否则在最坏的情况下,DR患者可能会导致失明。目前,DR是由医生使用手动方法使用视网膜眼底图像诊断的。与人工方法相比,自动化方法更可靠、更经济、更节省时间。在这项工作中,提出了一种深度学习(DL)模型,通过将视网膜眼底图像分为五个不同的类别来自动识别DR图像。使用了三种不同的深度学习预训练模型AlexNet, VGGNet和ResNet-18的混合深度学习模型。然后利用AdaBoost算法增强了组合模型的性能。AdaBoost算法用于挖掘不同深度学习模型之间的依赖关系。它可以处理缺失值和异常值。使用APTOS和Messidor-2数据集对所有预训练模型和建议模型进行训练。然后,根据性能指标准确性、灵敏度、特异性和F1score来评估所提出的混合深度学习模型以及其他三种预训练深度学习模型的性能。从得到的结果来看,值得注意的是,与其他预训练的深度学习模型相比,所提出的混合模型的性能度量值较高。因此,该方法是一种很有潜力的DR图像分类方法。
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