A controlled crossover study of triiodothyronine in autistic children.

M Campbell, A M Small, C S Hollander, J Korein, I L Cohen, M Kalmijn, S Ferris
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引用次数: 37

Abstract

A placebo-controlled crossover study of behavioral effects of triiodothyronine (T3) was conducted in 30 young clinically euthyroid autistic children. Multiple independent raters and multiple rating scales were used. Except for a few symptoms that were reduced on T3, the drug did not differ from placebo. Time itself accounted for most of the improvement in the whole sample. As a group, the lower IQ children responded to T3. The individual children who were responders could not be defined by any parameter.

自闭症儿童三碘甲状腺原氨酸的对照交叉研究。
对30例临床甲状腺功能正常的青少年自闭症儿童进行了三碘甲状腺原氨酸(T3)行为影响的安慰剂对照交叉研究。采用多个独立评价者和多个评价表。除了服用T3后症状有所减轻外,该药与安慰剂并无不同。时间本身是整个样本改善的主要原因。作为一个整体,智商较低的孩子对T3有反应。不能用任何参数来定义应答者的个体儿童。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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