Confidence intervals for odds ratio in matching pairs under inverse sampling

Abstract

Odds ratio is often used in matched pair design to assess the equivalence of two treatments for both prospective and retrospective clinical trials. In this context, we propose five confidence intervals estimator for the odds ratio in matching pairs under inverse sample. The performance of the proposed methods are evaluated with respect to their coverage probability and expected widths. Our empirical results show that the confidence interval based on the score statistic produce similar coverage probabilities and smaller confidence interval widths.