A Multi-Layer Parylene Electrode Array for Use in an Implantable Microsystem for Treatment of Neurological Disorders

C. Mousoulis, D. Papageorgiou
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Abstract

This paper presents a multi-layer parylene electrode array for neural recording and stimulation. The immediate targeted use is for cerebral surface recordings of patients suffering from epileptic seizures. Ultimately, it will serve as the neural interface portion of a larger, fully implantable system to be used in the treatment of neurological disorders such as Parkinson's disease, essential tremor and epilepsy. The probe array consists of a parylene-Ti-parylene structure with sites and pads formed by Ti/Au deposition. The use of Parylene-C provides flexibility and improved electrical and mechanical properties compared to conventional polymers. The probes were characterized in-vitro, exhibiting sufficiently low impedance, suitable for neural stimulation and recording.
用于神经系统疾病治疗的可植入微系统的多层聚对二甲苯电极阵列
提出了一种用于神经记录和刺激的多层聚对二甲苯电极阵列。直接的目标用途是癫痫发作患者的大脑表面记录。最终,它将作为一个更大的、完全可植入系统的神经接口部分,用于治疗神经系统疾病,如帕金森病、特发性震颤和癫痫。探针阵列由聚对二甲苯-钛-聚对二甲苯结构组成,其位和焊盘由Ti/Au沉积形成。与传统聚合物相比,聚苯乙烯- c的使用提供了灵活性和改进的电气和机械性能。该探针在体外具有足够低的阻抗,适合于神经刺激和记录。
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