Overview of Alzheimer's Disease

Abstract

Alzheimer's disease is a neurodegenerative disease that is more widespread worldwide, but there is currently no corresponding drug that can be effectively treated. The clinical phenomena of Alzheimer's disease mainly include memory disorders, cognitive disorders, language disorders and so on. There are many pathogeneses of Alzheimer's disease, such as Aβ toxicity theory, abnormal Tau protein metabolism, cholinergic theory, neuroinflammation theory, etc., but the most important theory is Aβ toxicity theory. In this paper, through the study of galanin, morphine, GABA and VEGF, it was found that the drug protects the brain cells and neurons by protecting Aβ neurotoxicity and reducing the apoptosis rate of cells. Although the above drugs can play a protective role in Aβ neurotoxicity, the treatment of clinical conditions specific to Alzheimer's disease needs further research. This article provides constructive suggestions for the research on the treatment of Alzheimer's disease.