Photoditazine mediated chemosensitized blood photomodification: advanced tumor treatment preliminary results

M. Gelfond, D. Vassiliev
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Abstract

Beside the classical photodynamic therapy (PDT) procedure, another possible mode of PDT treatment exists. In the latter case the light does not have to be delivered directly to tumor as soon as it is not always technically possible. In some cases systemic cytotoxic effects of photomodified blood can cause tumor damage. Possibly this happens due to apoptosis induction. These observations broaden possible PDT applications significantly.
光地嗪介导的化学致敏血液照相化:晚期肿瘤治疗的初步结果
除了经典的光动力治疗(PDT)程序外,存在另一种可能的PDT治疗模式。在后一种情况下,由于技术上不可能,光不必直接传递到肿瘤。在某些情况下,光照化血液的全身细胞毒性作用可引起肿瘤损伤。这可能是由于细胞凋亡的诱导。这些观察结果大大拓宽了PDT的应用范围。
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