A case of severe course of Sjögren's disease

Abstract

Sjögren's disease is a systemic disease of unknown etiology, a characteristic feature of which is a chronic autoimmune and lymphoproliferative process in the secreting epithelial glands with the development of parenchymatous sialadenitis with xerostomia and dry keratoconjunctivitis with hypolacrimia. Sjögren's syndrome is a lesion of the salivary and lacrimal glands similar to Sjögren's disease, which develops in 5-25% of patients with systemic connective tissue diseases, more often with rheumatoid arthritis, and in 50-75% of patients with chronic autoimmune liver damage (chronic autoimmune hepatitis, primary biliary cirrhosis) and less often in other autoimmune diseases.