Kronik Obstrüktif Akciğer Hastalığı Olan Hastalarda Komorbid Bronşektazinin Yaşam Kalitesine Etkisinin Değerlendirilmesi

Cansu Yılmaz, M. Acat, Serkan Öner, Habibe İnci, Didem Adahan
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Abstract

Objective: The objective of this study was to evaluate the effect of comorbid bronchiectasis on quality-of-life in patients with Chronic Obstructive Pulmonary Disease (COPD). Method: 103 patients were diagnosed with COPD were included in our study. Spirometric measurements were made. The following measurement tools were used to collect data: 6-Minute Walk Test (6MWT), Modified Medical Research Council (mMRC) dyspnea scale, COPD Assessment Test (CAT), St. George Respiratory Questionnaire (SGRQ), and Short Form 36 (SF-36) quality-of-life questionnaire. Furthermore, all the patients’ high Resolution Computed Tomography (HRCT) images for the last three years were included in the study. Result: 93.2% of the patients were male, with a mean age of 64.79±9.35 years. It was found that SGRQ and SF-36 quality-of-life scores decreased by half in all the patients compared to normal ones. The volume/forced vital capacity (FEV1/FVC) values in the first second of forced expiration were significantly lower in the group with bronchiectasis. A significant correlation was found to exist between the patients’ mMRC dyspnea scale and CAT scores, 6MWT distances, and all subscales of SGRQ and SF-36. In addition, a significant correlation was also found to exist between FEV1 values and all subscales of SGRQ, and between subscales of SF-36. Conclusion: In our study, when we compared the quality-of-life scores of the patients with COPD and bronchiectasis with those with COPD alone, we found that the quality-of-life of both groups was impaired, but there was no significant difference between them.
目的:本研究的目的是评估合并支气管扩张对慢性阻塞性肺疾病(COPD)患者生活质量的影响。方法:103例慢性阻塞性肺病患者纳入研究。进行肺活量测定。采用以下测量工具收集数据:6分钟步行测试(6MWT)、改良医学研究委员会(mMRC)呼吸困难量表、COPD评估测试(CAT)、St. George呼吸问卷(SGRQ)和SF-36生活质量问卷。此外,所有患者近三年的高分辨率计算机断层扫描(HRCT)图像均被纳入研究。结果:93.2%的患者为男性,平均年龄64.79±9.35岁。研究发现,与正常患者相比,所有患者的SGRQ和SF-36生活质量评分下降了一半。支气管扩张组肺活量/用力肺活量(FEV1/FVC)值在强迫呼气第一秒明显降低。患者的mMRC呼吸困难量表与CAT评分、6MWT距离、SGRQ和SF-36各亚量表均存在显著相关。此外,FEV1值与SGRQ各子量表、SF-36子量表之间也存在显著的相关性。结论:在我们的研究中,当我们将COPD合并支气管扩张患者的生活质量评分与单纯COPD患者的生活质量评分进行比较时,我们发现两组患者的生活质量均受损,但两者之间无显著差异。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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