Plasma fibrinogen in preeclampsia pregnancy

Abstract

The aims of this study are the evaluation of serum Fibrinogen in preeclampsia and healthy controls; and the relation of Fibrinogen with hypertension. 90 subjects were incorporated in this study, 30 were healthy control with mean age 35.6 years. 60 Preeclampsia case with mean age 32-65 years preeclampsia, wherever all women were more 20 weeks of pregnancy. The blood was separated by centrifuge for evaluation coagulation profile levels and lipid profile. The findings were showed serum Fibrinogen was significantly decreased in preeclampsia than normal (p< 0.005), Systolic blood pressure was significantly varied among preeclampsia group (p < 0.001). Concerning the lipid profile, only TC was significantly increased in preeclampsia patients than control p < 0.0001 while no significant variations in lipid profile were observed between the two pregnant groups. The Fibrinogen is a good indicator for the detection of preeclampsia in pregnant women. New tests are needed for determining the concentration of Fibrinogen in the pregnancy stages.