Effectiveness of Luliconazole for the Treatment of Tinea Infections: A Retrospective Study

P. Kumari, Nitin Jain
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Abstract

Background: Real-world evidence supporting luliconazole is needed to strengthen the usage of luliconazole for the treatment of dermatophyte infections. Objective: To evaluates the effectiveness of luliconazole in real-world settings. Methods: This is a retrospective, EMR based study conducted on 145 patients with tinea infections treated with luliconazole 1% cream for four weeks, and the effectiveness was assessed at the end treatment. Results: Of 145 patients, 115 (79.31%) had Tinea cruris, and the treatment outcome for 138 (95.17%) was recorded as recovered significantly (p-value <0.05). Fifty-one (96.23%) females and 87 (94.57%) males recovered from the infections during treatment period. A 100% recovery rate observed among patients aged 46-60 years. Of 88 patients below 30 years, 82 (93.18%) recovered, while 44 (97.78%) patients recovered in the age group of 31-45 years. Conclusion: Within the limitations of the current study, luliconazole demonstrated effectiveness in treating Tinea corporis, Tinea cruris, and Tinea pedis infections.
吕立康唑治疗足癣感染的疗效:回顾性研究
背景:需要真实世界的证据支持露立康唑,以加强使用露立康唑治疗皮肤真菌感染。目的:评价露立康唑在现实生活中的有效性。方法:本研究是一项基于EMR的回顾性研究,对145例1%露立康唑乳膏治疗4周的癣感染患者进行研究,并在治疗结束时评估疗效。结果:145例患者中,115例(79.31%)出现癣,138例(95.17%)疗效显著(p值<0.05)。治疗期间,女性51例(96.23%)、男性87例(94.57%)痊愈。46 ~ 60岁患者康复率100%。88例30岁以下患者痊愈82例(93.18%),31 ~ 45岁患者痊愈44例(97.78%)。结论:在当前研究的限制范围内,luliconazole在治疗体癣、股癣和足癣感染方面显示出有效性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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