Development of a Compact X-ray PIV System and New X-ray Flow Tracers - Visualization of Opaque Biofluid Flows using X-ray PIV System

S. Lee, S. Jung
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Abstract

A compact X-ray particle image velocimetry (PIV) system employing a medical X-ray tube as a light source was developed to obtain quantitative velocity field information of opaque flows. The X-ray PIV system consists of a medical X-ray tube, an X-ray CCD camera, a programmable shutter for generating a pulse-type X-ray beam, and a synchronization device. Through performance tests, the feasibility of the developed Xray PIV system as a flow measuring device was verified. In applying the developed system to biofluid flows, the most important prerequisite is to develop suitable flow tracers which should be detected clearly by the X-ray imaging system. Iopamidol was encapsulated into the poly(vinyl alcohol) (PVA) microparticles to fabricate such flow tracers. The characteristics of the fabricated microparticles were checked. With increasing the amount of crosslinker, the degree of crosslinking and the efficiency of the Iopamidol encapsulation were increased. This compact X-ray PIV system is a unique and useful for investigating various biofluid flows in laboratory experiments.
紧凑型x射线PIV系统和新型x射线流动示踪剂的开发——利用x射线PIV系统可视化不透明生物流体流动
研制了一种以医用x射线管为光源的小型x射线粒子图像测速系统(PIV),用于获取不透明流的定量速度场信息。x射线PIV系统由一个医用x射线管、一个x射线CCD相机、一个用于产生脉冲型x射线束的可编程快门和一个同步装置组成。通过性能测试,验证了所研制的x射线PIV系统作为流量测量装置的可行性。在将所开发的系统应用于生物流体流动时,最重要的先决条件是开发合适的流动示踪剂,这些示踪剂应被x射线成像系统清晰地检测到。将Iopamidol包封在聚乙烯醇(PVA)微粒中,制备了这种流动示踪剂。对制备的微颗粒进行了特性检测。交联剂用量越大,交联度越高,碘帕美醇包封效率越高。这种紧凑的x射线PIV系统是一个独特的和有用的研究各种生物流体流动的实验室实验。
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