A review focusing on the benefits of green tea catechins as nutraceuticals

N. Naware, Shreya Ambatkar, T. Kamble, Sonal Bangar, Kiran Uppar, Kshitij Shirke, M. Patil, Ashish Jain
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Abstract

Any product generated from food sources that offer additional health advantages over and above the essential nutritional content present in foods is referred to as a nutraceutical under the broad umbrella term. The catechins in Camellia sinensis (Theaceae) namely (-)-epicatechin, (-)-epicatechin-3-gallate, (-)-epigallocatechin, and (-)-epigallocatechin-3-gallate (EGCG), which can be used as nutraceuticals in food or as a component of food items has been discussed. Catechins being polyphenols and antioxidants are found to have a wide range of therapeutic application like weight loss, anticancer, anti-inflammatory, and a few more therapeutic applications, through various mechanisms like stimulating AMP-activated protein kinase, enhanced apoptosis, decreased expression of interleukin (IL)-6 and IL-8. The most recent method for extracting catechins include combining the extraction processing of PEF or IPL with Subcritical water extraction. Food additives have been mixed with green tea extracts to develop a desired formulation like chewing gum and capsule. As green tea catechins are a beneficial phytoconstituents to improve overall health, its prospects include formulation of a gelatin gummy formulation which will improve its palatability by masking the bitter taste. Gelatin gummy formulation can be carried conveniently and will provide easy access to the consumer as compared to green tea. Furthermore, we found a scope to develop an analytical method for EGCG and carry out its validation by HPLC which will be more reliable and cost-efficient in comparison to the existing UHPLC methods for EGCG.
综述了绿茶儿茶素作为保健品的益处
任何从食物中产生的产品,在食品中存在的基本营养成分之上提供额外的健康益处,都被称为营养保健品。讨论了山茶中的儿茶素(-)-表儿茶素、(-)-表儿茶素-3-没食子酸酯、(-)-表没食子儿茶素和(-)-表没食子儿茶素-3-没食子酸酯(EGCG),它们可作为食品中的营养品或食品成分。儿茶素是一种多酚和抗氧化剂,被发现具有广泛的治疗应用,如减肥、抗癌、抗炎,以及一些更多的治疗应用,通过各种机制,如刺激amp活化的蛋白激酶、增强细胞凋亡、降低白细胞介素(IL)-6和IL-8的表达。最近的一种提取儿茶素的方法是将PEF或IPL的提取工艺与亚临界水萃取相结合。食品添加剂与绿茶提取物混合,形成一种理想的配方,如口香糖和胶囊。由于绿茶儿茶素是一种有益的植物成分,可以改善整体健康,其前景包括明胶胶配方,通过掩盖苦味来改善其适口性。与绿茶相比,明胶胶配方可以方便地携带,并且可以方便地接触到消费者。此外,我们发现了开发EGCG分析方法并通过HPLC进行验证的范围,与现有的UHPLC方法相比,该方法更可靠,更具成本效益。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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