Sensitization to Food and Aeroallergens in Patients with Asthma, Allergic Rhinitis, Eczema and Urticaria

Abbas Dabbaghzadeh, J. Ghaffari, J. Yazdani-charati, Marziyeh Mohammadi Kordkheyli, Fatemeh Pouresmaeil
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Abstract

Background and Aims: Allergic disorders such as asthma, urticaria, eczema, and allergic rhinitis are common worldwide, and allergens are the most common etiology and exacerbating factors. So, This study aimed to find the allergens in these patients with skin prick tests. Materials and Methods: All the allergic cases referred to an allergic clinic in the north of Iran were visited by an allergist and clinical immunologist. Based on patient history, physical examination, and diagnosis, we select food allergens and aeroallergens. A standard skin prick test was performed on all patients, and all data was then analyzed SPSS 20. Results: Two thousand one hundred and twenty-eight cases entered the study with a mean age of 27.65 ± 15.52 years old. 1235 (58.04%) females and 893 males (41.96%) participated in this study. Prevalence of allergic rhinitis, asthma, urticaria, and eczema were 717 (33.7%), 611 (28.8%), 550 (25.8%), and 250 (11.7%), respectively. The most common aeroallergens were Dermatophagoides farinae (75.9%), Dermatophagoides pteronyssinus  (65.4%), feather (56.1%), and Candida (51.1%), respectively, in all patients. The most common food allergens were egg white (31.1%), cacao (29.7%), and egg yolk (28.9%), respectively, in all cases. Conclusion: Both aeroallergens and food allergens were the most common in all allergens by skin prick test. Therefore, it is important to find the relationship between sensitization and allergy.
哮喘、变应性鼻炎、湿疹和荨麻疹患者对食物和空气过敏原的致敏
背景和目的:过敏性疾病如哮喘、荨麻疹、湿疹和变应性鼻炎在世界范围内很常见,而过敏原是最常见的病因和加重因素。因此,本研究旨在通过皮肤点刺试验发现这些患者的过敏原。材料和方法:所有转到伊朗北部过敏诊所的过敏病例均由过敏专科医生和临床免疫学家访问。根据病人的病史、体格检查和诊断,我们选择食物过敏原和空气过敏原。所有患者均进行标准皮肤点刺试验,并用SPSS 20对所有数据进行分析。结果:入组病例2128例,平均年龄27.65±15.52岁。女性1235人(58.04%),男性893人(41.96%)。变应性鼻炎、哮喘、荨麻疹、湿疹患病率分别为717例(33.7%)、611例(28.8%)、550例(25.8%)、250例(11.7%)。在所有患者中,最常见的空气过敏原分别为粉状棘球蚴(75.9%)、翼状棘球蚴(65.4%)、羽毛(56.1%)和念珠菌(51.1%)。在所有病例中,最常见的食物过敏原分别是蛋清(31.1%)、可可(29.7%)和蛋黄(28.9%)。结论:皮肤点刺试验结果显示,空气过敏原和食物过敏原在所有过敏原中最常见。因此,寻找致敏与过敏之间的关系是非常重要的。
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