Novel Multibiosensors and Biomedical Application

A. Tashtoush
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引用次数: 4

Abstract

Annually, a lot of patients in Canadian hospitals are contaminated with antibiotic-resistant bacteria, resulting in abundant amounts of money spent on the health-care system. Even though most bacteria are risk-free to healthy individuals, the symptoms of bacterial contamination can be severe for patients with a weakened immune system. Early detection is critical for improved patient care and can help in minimizing the risk of cross contamination between patients. This work aims at using state-of-the-art technologies for developing handheld multibiosensors on a single chip for pathogenic bacteria detection. There is extensive demand for a low-cost, rapid, selective and sensitive method for detecting bacteria in medical diagnosis, and food-safety inspection. In this work, we are introducing more than one technique based on a CMOS/MEMS technology batch process for detecting pathogen bacterial cell at a low concentration level. The methodology of the proposed multi-labs-on-a-single-chip system (MLoC) lies on miniaturizing transducers, which is utilizing a sort of technique that has the capability to smooth the progress of point-of-care testing (POCT) and become conscious state-of-the-art molecular analysis independently of the state-of-the-art laboratory. MLoC methodology can be categorized as electrochemical, capacitive and optical, on the light of their sensing theory, incorporated with interdigitated microelectrode array (IDMA).
新型多生物传感器及其生物医学应用
每年,加拿大的医院里都有很多病人被抗生素耐药性细菌污染,导致医疗保健系统花费了大量的钱。尽管大多数细菌对健康人是无害的,但对于免疫系统较弱的患者来说,细菌污染的症状可能很严重。早期发现对于改善患者护理至关重要,并有助于最大限度地减少患者之间交叉污染的风险。这项工作的目的是利用最先进的技术,在单芯片上开发手持式多生物传感器,用于病原菌检测。在医学诊断和食品安全检测中,对低成本、快速、选择性和敏感的细菌检测方法有着广泛的需求。在这项工作中,我们介绍了多种基于CMOS/MEMS技术的批量工艺,用于检测低浓度水平的病原体细菌细胞。所提出的单芯片多实验室系统(MLoC)的方法在于小型化传感器,它利用了一种技术,能够平滑点护理测试(POCT)的进展,并独立于最先进的实验室成为有意识的最先进的分子分析。MLoC方法根据其传感理论可分为电化学、电容和光学,并结合了交叉指状微电极阵列(IDMA)。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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