Leki recepturowe do ucha stosowane w codziennej praktyce otorynolaryngologicznej u pacjentów pediatrycznych i dorosłych – możliwości, wskazania, wyzwania

Kajetany Instytut Narządów Zmysłów, Kajetany
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Abstract

Introduction: In ENT practice ear and nose drops, solutions (iontophoresis), mixtures (for gargling) and nose and ear ointments are the most popular compounding medicines in ENT diseases. Advantages of compounding medicines are lack of or limit dye substances, preservatives, fragrances what is important for pediatric population and allergic persons. Additionally, the dose of active ingredient may be adjusted to weight and age of patient. That is important when there is lack of finished medical product in pharmaceutical market. complex overview of publications in medical bases such as: Scopus, Embase, ScienceDirect, PubMed with the searching sentences: ear + compounding + medication, ENT + compounding + medication, compounding + drugs + ENT. Results: Active ingredients used in compounding medications are: anti-inflammatory substances (hydrocortisonum, prednisolone), antibacterial substances (metronidazole), antifungal (nystatin, clotrimazole), local anesthetics (tetracaine, benzocaine) and menthol, thymol, peppermint oil, boric acid or glycerol. Conclusions: Compounding medications in ENT are used in otitis externa due to limited access of finished medical products.
简介:在耳鼻喉科实践中,耳鼻喉科疾病最常用的复合药物是耳鼻滴剂、溶液(离子导入)、混合物(用于漱口)和鼻耳软膏。复合药物的优点是缺乏或限制染料物质,防腐剂,香料,这对儿科人群和过敏人群很重要。此外,活性成分的剂量可根据患者的体重和年龄进行调整。在医药市场缺乏成品的情况下,这一点很重要。对Scopus, Embase, ScienceDirect, PubMed等医学基地的出版物进行综合综述,检索语句:ear + compound + medication, ENT + compound + medication, compound + drugs + ENT。结果:复方药物的有效成分有:抗炎物质(氢化可的松、强的松龙)、抗菌物质(甲硝唑)、抗真菌物质(制霉菌素、克霉唑)、局部麻醉剂(丁卡因、苯佐卡因)和薄荷醇、百里香酚、薄荷油、硼酸或甘油。结论:耳鼻喉科的复方药物治疗外耳炎,由于药物成品的可及性有限。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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