Relation of plasma noradrenaline to blood pressure, age, sex and sodium balance in patients with stable essential hypertension and in normotensive subjects.

H M Brecht, W Schoeppe
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引用次数: 36

Abstract

1. Plasma noradrenaline was measured in 125 patients with stable essential hypertension (WHO I-II) and in 107 normotensive control subjects lying and standing. 2. In normotensive subjects and in patients with essential hypertension no sex-related differences of plasma noradrenaline were found between age-matched groups. 3. Plasma noradrenaline was not related to sodium balance indexed by urinary sodium/creatinine ratio. 4. In patients with essential hypertension plasma noradrenaline increases with age. 5. Mean plasma noradrenaline concentrations are significantly higher in patients with essential hypertension compared with age-matched normotensive subjects both lying and standing. 6. In patients with essential hypertension diastolic blood pressure and heart rate correlated significantly with supine plasma noradrenaline concentrations.

血浆去甲肾上腺素与稳定期高血压患者及正常血压者血压、年龄、性别及钠平衡的关系
1. 测定125例稳定型原发性高血压(WHO I-II)患者和107例正常血压对照者的血浆去甲肾上腺素水平。2. 在血压正常的受试者和原发性高血压患者中,血浆去甲肾上腺素在年龄匹配组之间没有性别相关的差异。3.血浆去甲肾上腺素与尿钠/肌酐比值指示的钠平衡无关。4. 原发性高血压患者血浆去甲肾上腺素随年龄增加而升高。5. 原发性高血压患者的平均血浆去甲肾上腺素浓度明显高于与年龄匹配的血压正常者,无论是躺着还是站着。6. 原发性高血压患者舒张压和心率与仰卧位血浆去甲肾上腺素浓度显著相关。
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