Advances in Clinical Practice, Diagnosis and Treatment of Chronic Chagas’ Heart Disease

Sílvia Marinho Martins Alves, Bárbara Mariana dos Santos Silva, Esthefany Dias Barbosa, C. Medeiros, M. D. N. D. S. Barros, M. Cavalcanti, Maria Elisa Lucena Sales de Melo Assunção, Virginia Lorena, A. Albuquerque, Renata Amorim de Lucena, C. Montenegro, C. B. Pereira, Lucas Reis da Costa, C. Carrazzone, W. Oliveira
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Abstract

Chagas disease has become globalized as a result of the migratory process of infected patients to non-endemic areas. With the considerable number of individuals affected by the disease, detection and treatment of its chronic manifestations is a relevant and necessary issue. Growing attention has been paid to chronic Chagas cardiomyopathy (CCC), which includes heart failure, malignant arrhythmias, conduction disturbances and thromboembolic events. Many pharmacological and non-pharmacological treatments for CCC are still extrapolations of existing evidence on the treatment of other clinical conditions, highlighting the need of including this group of patients in future studies. In this review, we will discuss the most recent data from the literature and clinical practice on the diagnosis and treatment of CCC.
慢性恰加斯病的临床实践及诊治进展
由于受感染患者向非流行地区的迁移过程,恰加斯病已变得全球化。由于有相当多的人受到该病的影响,检测和治疗其慢性表现是一个相关和必要的问题。慢性恰加斯心肌病(CCC)包括心力衰竭、恶性心律失常、传导障碍和血栓栓塞事件,已受到越来越多的关注。CCC的许多药物和非药物治疗仍然是对其他临床疾病治疗的现有证据的推断,这突出了在未来的研究中包括这组患者的必要性。在这篇综述中,我们将讨论从文献和临床实践中关于CCC诊断和治疗的最新数据。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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