COMPUTER ELECTROACUPUNCTURE FOR IRRITABLE BOWEL SYNDROME: EFFICACY AND SEARCH FOR EFFICACY PREDICTORS

M.P. Khokhlov, A. B. Peskov, N. N. Klimova, T.S. Golubtsova, S.A. Pribylova, I.R. Kerova, E. Yudina
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引用次数: 1

Abstract

Non-pharmacological treatment modalities, in particular, a new technique in reflexology – computerized electroacupuncture (CEAP), allow us to increase the efficacy while treating patients with irritable bowel syndrome (IBS). Search for predictors of CEAP efficacy in IBS will optimize the choice of patients for treatment, improving the CEAP efficacy profile. The aim of the study is to evaluate CEAP efficacy in the complex therapy of various clinical IBS forms. Materials and Methods. The study involved 80 IBS patients. Patients of the main group underwent three courses of CEAP in addition to standard pharmacological therapy, patients of the reference group received only pharmacotherapy. At the beginning and at the end of each CEAP course, the severity of pain syndrome (visual analogue scale), stool frequency, stool consistency (Bristol stool scale), and subjective state indicators (Zung Self-Rating Depression Scale, Spielberger-Khanin test) were assessed. A retrospective analysis of the research results was carried out to search for predictors of CEAP efficacy. The impact of such parameters as patient’s gender, age, disease form and severity on treatment outcome was assessed. Results. After the first CEAP, the severity of abdominal pain in patients of the main group decreased from 6.1 mm to 3.9 mm and after the third CEAP to 3.7 mm. After three courses of CEAP, defecation frequency in IBS patients with diarrhea decreased from 4.7 to 1.9 per day, and in IBS patients with constipation increased from 0.26 to 0.77 per day. The proportion of patients with normal stool consistency increased significantly both among patients with constipation and among those with diarrhea to 47.1 and 55.6 %, respectively. Retrospective analysis showed the best treatment results in patients with mild and moderate IBS.
计算机电针治疗肠易激综合征:疗效和疗效预测因子的研究
非药物治疗方式,特别是反射疗法中的一项新技术——计算机电针(CEAP),使我们在治疗肠易激综合征(IBS)患者时提高了疗效。寻找CEAP对IBS疗效的预测因子将优化患者的治疗选择,改善CEAP的疗效概况。该研究的目的是评估CEAP在各种临床IBS形式的综合治疗中的疗效。材料与方法。这项研究涉及80名肠易激综合征患者。主组患者在标准药物治疗的基础上进行三个疗程的CEAP治疗,参照组患者仅接受药物治疗。在每个CEAP课程开始和结束时,评估疼痛综合征的严重程度(视觉模拟量表)、大便频率、大便一致性(Bristol大便量表)和主观状态指标(Zung抑郁自评量表、Spielberger-Khanin测试)。对研究结果进行回顾性分析,以寻找CEAP疗效的预测因素。评估患者性别、年龄、疾病形式、严重程度等参数对治疗结果的影响。结果。第一次CEAP后,主组患者腹痛严重程度由6.1 mm降至3.9 mm,第三次CEAP后降至3.7 mm。经过三个疗程的CEAP治疗,腹泻IBS患者的排便次数从每天4.7次下降到1.9次,便秘IBS患者的排便次数从每天0.26次增加到0.77次。大便粘稠度正常的患者比例在便秘患者和腹泻患者中均显著增加,分别达到47.1%和55.6%。回顾性分析显示,轻、中度IBS患者的治疗效果最好。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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