Real-time study of adenosine-5' monophosphate adsorption with a Love wave sensor based on molecularly imprinted polymer

Abstract

In this paper, we present a study of real-time adsorption on thin film Molecularly imprited polymer (MIP) coating based on commercial nucleotides Adenosine Mono Phosphate (AMP). The MIP sensitive layer is deposited on top of the propagation path of a Love wave sensor. Detection tests of different concentrations of AMP have been performed in aqueous media through a microfluidic chip placed above the delay line. Real time sensor's response was recorded in terms of frequency shift using an oscillating configuration setup. A frequency shift of 150 Hz was recorded for 5 ppm AMP concentration.