Nanocomposite hydrogels : A novel wound dressings

Abstract

This A novel class of nanocomposite hydrogels (NC gels) with a unique organic / inorganic network structure was synthesized by insitu free-radical polymerization of N-isopropylacrylamide (NIPA) or N,N-dimethylacrylamide (DMAA) in the presence of inorganic clay (hectorite). Here, we investigated the effect of NC gel films on the healing of artificial wounds in adult goats. Our results indicate that NC gel films improved the healing rate of artificial wounds in adult goats. We also obtained a good clinical outcome in the treatment of a poorly healing pressure leg ulcer wound of bovine. Thus, NC gel should be a candidate for wound care.